Marco Estrada gave up one hit through seven stellar innings and Caleb Gindl slugged an early two-run homer, as Milwaukee topped Cincinnati, 3-0, in the rubber match of a three-game series.
Estrada (6-4) turned in one of the best performances of his career, fanning nine and walking two en route to his second positive decision in three starts.
Jean Segura finished with two hits and drove in the other run for the Brewers, who have won three of five overall.
Selected from Triple-A Louisville prior to the game, Greg Reynolds (0-2) lasted six full frames, giving up two runs on five hits in the loss for the Reds, who were coming off a series win against Arizona.
Joey Votto's ninth-inning homer stood as Cincinnati's only meaningful offense.
The Brewers are off on Monday, and begin a series in Pittsburgh on Tuesday night at 5:30pm CT on AM-550 FM-99.9 WSAU.